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Yin and Yang of disease genes and death genes between reciprocally scale-free biological networks

Biological networks often show a scale-free topology with node degree following a power-law distribution. Lethal genes tend to form functional hubs, whereas non-lethal disease genes are located at the periphery. Uni-dimensional analyses, however, are flawed. We created and investigated two distinct...

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Detalles Bibliográficos
Autores principales: Han, Hyun Wook, Ohn, Jung Hun, Moon, Jisook, Kim, Ju Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814386/
https://www.ncbi.nlm.nih.gov/pubmed/23935122
http://dx.doi.org/10.1093/nar/gkt683