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Metal ion as both a cofactor and a probe of metal-binding sites in a uranyl-specific DNAzyme: a uranyl photocleavage study

DNAzymes are known to bind metal ions specifically to carry out catalytic functions. Despite many studies since DNAzymes were discovered nearly two decades ago, the metal-binding sites in DNAzymes are not fully understood. Herein, we adopt uranyl photocleavage to probe specific uranyl-binding sites...

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Detalles Bibliográficos
Autores principales: Cepeda-Plaza, Marjorie, Null, Eric L., Lu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814387/
https://www.ncbi.nlm.nih.gov/pubmed/23939617
http://dx.doi.org/10.1093/nar/gkt694