PCNA promotes processive DNA end resection by Exo1

Exo1-mediated resection of DNA double-strand break ends generates 3′ single-stranded DNA overhangs required for homology-based DNA repair and activation of the ATR-dependent checkpoint. Despite its critical importance in inducing the overall DNA damage response, the mechanisms and regulation of the...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoqing, Paudyal, Sharad C., Chin, Re-I, You, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814391/
https://www.ncbi.nlm.nih.gov/pubmed/23939618
http://dx.doi.org/10.1093/nar/gkt672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814391/
https://www.ncbi.nlm.nih.gov/pubmed/23939618
http://dx.doi.org/10.1093/nar/gkt672

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