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Global Population Structure of the Genes Encoding the Malaria Vaccine Candidate, Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1)

BACKGROUND: The Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1) is a promising malaria vaccine candidate, however it remains unclear which regions are naturally targeted by host immunity and whether its high genetic diversity will preclude coverage by a monovalent vaccine. To assess its feasibil...

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Detalles Bibliográficos
Autores principales: Arnott, Alicia, Mueller, Ivo, Ramsland, Paul A., Siba, Peter M., Reeder, John C., Barry, Alyssa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814406/
https://www.ncbi.nlm.nih.gov/pubmed/24205419
http://dx.doi.org/10.1371/journal.pntd.0002506