Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and Immunotypes

Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to rationally develop an HIV-1 vaccine. We previously identified a participant in the CAPRISA Acute Infection Cohort (CAP257) whose plasma neutralize...

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Detalles Bibliográficos
Autores principales: Wibmer, Constantinos Kurt, Bhiman, Jinal N., Gray, Elin S., Tumba, Nancy, Abdool Karim, Salim S., Williamson, Carolyn, Morris, Lynn, Moore, Penny L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814426/
https://www.ncbi.nlm.nih.gov/pubmed/24204277
http://dx.doi.org/10.1371/journal.ppat.1003738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814426/
https://www.ncbi.nlm.nih.gov/pubmed/24204277
http://dx.doi.org/10.1371/journal.ppat.1003738

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