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Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and Immunotypes
Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to rationally develop an HIV-1 vaccine. We previously identified a participant in the CAPRISA Acute Infection Cohort (CAP257) whose plasma neutralize...
Autores principales: | Wibmer, Constantinos Kurt, Bhiman, Jinal N., Gray, Elin S., Tumba, Nancy, Abdool Karim, Salim S., Williamson, Carolyn, Morris, Lynn, Moore, Penny L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814426/ https://www.ncbi.nlm.nih.gov/pubmed/24204277 http://dx.doi.org/10.1371/journal.ppat.1003738 |
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