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Using Systems Biology-based Analysis Approaches to Identify Mechanistically Significant Adverse Drug Reactions: Pulmonary Complications from Combined Use of Anti-TNFα Agents and Corticosteroids

Anti-TNF drugs are frequently associated with serious Adverse Events (AEs), which necessitates an improved understanding of individual factors that determine efficacy and safety of anti-TNF agents. We mined the US FDA’s Adverse Event Reporting System (AERS) for anti-TNF-associated AEs to identify an...

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Detalles Bibliográficos
Autores principales: Sarangdhar, Mayur, Kushwaha, Akash, Dahlquist, Jeanine, Jegga, Anil, Aronow, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814486/
https://www.ncbi.nlm.nih.gov/pubmed/24303326