LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7

The RNA-binding proteins LIN28A and LIN28B have diverse functions in embryonic stem cells, cellular reprogramming, growth, and oncogenesis. Many of these effects occur via direct inhibition of Let-7 microRNAs (miRNAs), although Let-7-independent effects have been surmised. We report that intestine t...

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Detalles Bibliográficos
Autores principales: Madison, Blair B., Liu, Qi, Zhong, Xue, Hahn, Christopher M., Lin, Nan, Emmett, Matthew J., Stanger, Ben Z., Lee, Ju-Seog, Rustgi, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814644/
https://www.ncbi.nlm.nih.gov/pubmed/24142874
http://dx.doi.org/10.1101/gad.224659.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814644/
https://www.ncbi.nlm.nih.gov/pubmed/24142874
http://dx.doi.org/10.1101/gad.224659.113

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