Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle

Endogenous BRCA1 p220 expression peaks in S and G2 when it is activated, and the protein participates in certain key DNA damage responses. In contrast, its expression is markedly reduced in G0/G1. While variations in transcription represent a significant part of p220 expression control, there is at...

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Detalles Bibliográficos
Autores principales: Dimitrov, Stoil D., Lu, David, Naetar, Nana, Hu, Yiduo, Pathania, Shailja, Kanellopoulou, Chryssa, Livingston, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814647/
https://www.ncbi.nlm.nih.gov/pubmed/24142877
http://dx.doi.org/10.1101/gad.225045.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814647/
https://www.ncbi.nlm.nih.gov/pubmed/24142877
http://dx.doi.org/10.1101/gad.225045.113

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