Penton-Dodecahedral Particles Trigger Opening of Intercellular Junctions and Facilitate Viral Spread during Adenovirus Serotype 3 Infection of Epithelial Cells

Human adenovirus serotypes Ad3, Ad7, Ad11, and Ad14 use the epithelial junction protein desmoglein 2 (DSG2) as a receptor for infection. During Ad infection, the fiber and penton base capsid proteins are produced in vast excess and form hetero-oligomers, called pentons. It has been shown for Ad3 tha...

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Detalles Bibliográficos
Autores principales: Lu, Zhuo-Zhuang, Wang, Hongjie, Zhang, YiYi, Cao, Hua, Li, Zongyi, Fender, Pascal, Lieber, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814681/
https://www.ncbi.nlm.nih.gov/pubmed/24204268
http://dx.doi.org/10.1371/journal.ppat.1003718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814681/
https://www.ncbi.nlm.nih.gov/pubmed/24204268
http://dx.doi.org/10.1371/journal.ppat.1003718

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