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Penton-Dodecahedral Particles Trigger Opening of Intercellular Junctions and Facilitate Viral Spread during Adenovirus Serotype 3 Infection of Epithelial Cells
Human adenovirus serotypes Ad3, Ad7, Ad11, and Ad14 use the epithelial junction protein desmoglein 2 (DSG2) as a receptor for infection. During Ad infection, the fiber and penton base capsid proteins are produced in vast excess and form hetero-oligomers, called pentons. It has been shown for Ad3 tha...
Autores principales: | Lu, Zhuo-Zhuang, Wang, Hongjie, Zhang, YiYi, Cao, Hua, Li, Zongyi, Fender, Pascal, Lieber, André |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814681/ https://www.ncbi.nlm.nih.gov/pubmed/24204268 http://dx.doi.org/10.1371/journal.ppat.1003718 |
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