Metabolic Activation of the Tumorigenic Pyrrolizidine Alkaloid, Retrorsine, Leading to DNA Adduct Formation In Vivo

Pyrrolizidine alkaloids are naturally occurring genotoxic chemicals produced by a large number of plants. The high toxicity of many pyrrolizidine alkaloids has caused considerable loss of free-ranging livestock due to liver and pulmonary lesions. Chronic exposure of toxic pyrrolizidine alkaloids to...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yu-Ping, Fu, Peter P., Chou, Ming W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814699/
https://www.ncbi.nlm.nih.gov/pubmed/16705803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814699/
https://www.ncbi.nlm.nih.gov/pubmed/16705803

Ejemplares similares