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Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin

Unlike the majority of actinomycete secondary metabolic pathways, the biosynthesis of peptidoglycan glycosyltransferase inhibitor moenomycin in Streptomyces ghanaensis does not involve any cluster-situated regulators (CSRs). This raises questions about the regulatory signals that initiate and sustai...

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Detalles Bibliográficos
Autores principales: Makitrynskyy, Roman, Ostash, Bohdan, Tsypik, Olga, Rebets, Yuriy, Doud, Emma, Meredith, Timothy, Luzhetskyy, Andriy, Bechthold, Andreas, Walker, Suzanne, Fedorenko, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814723/
https://www.ncbi.nlm.nih.gov/pubmed/24153004
http://dx.doi.org/10.1098/rsob.130121