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RNA–DNA differences in human mitochondria restore ancestral form of 16S ribosomal RNA

RNA transcripts are generally identical to the underlying DNA sequences. Nevertheless, RNA–DNA differences (RDDs) were found in the nuclear human genome and in plants and animals but not in human mitochondria. Here, by deep sequencing of human mitochondrial DNA (mtDNA) and RNA, we identified three R...

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Detalles Bibliográficos
Autores principales: Bar-Yaacov, Dan, Avital, Gal, Levin, Liron, Richards, Allison L., Hachen, Naomi, Rebolledo Jaramillo, Boris, Nekrutenko, Anton, Zarivach, Raz, Mishmar, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814879/
https://www.ncbi.nlm.nih.gov/pubmed/23913925
http://dx.doi.org/10.1101/gr.161265.113