Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation

Most methods for next-generation sequencing (NGS) data analyses incorporate information regarding allele frequencies using the assumption of Hardy–Weinberg equilibrium (HWE) as a prior. However, many organisms including those that are domesticated, partially selfing, or with asexual life cycles show...

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Detalles Bibliográficos
Autores principales: Vieira, Filipe G., Fumagalli, Matteo, Albrechtsen, Anders, Nielsen, Rasmus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814885/
https://www.ncbi.nlm.nih.gov/pubmed/23950147
http://dx.doi.org/10.1101/gr.157388.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814885/
https://www.ncbi.nlm.nih.gov/pubmed/23950147
http://dx.doi.org/10.1101/gr.157388.113

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