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Defining cell-type specificity at the transcriptional level in human disease

Cell-lineage–specific transcripts are essential for differentiated tissue function, implicated in hereditary organ failure, and mediate acquired chronic diseases. However, experimental identification of cell-lineage–specific genes in a genome-scale manner is infeasible for most solid human tissues....

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Detalles Bibliográficos
Autores principales: Ju, Wenjun, Greene, Casey S., Eichinger, Felix, Nair, Viji, Hodgin, Jeffrey B., Bitzer, Markus, Lee, Young-suk, Zhu, Qian, Kehata, Masami, Li, Min, Jiang, Song, Rastaldi, Maria Pia, Cohen, Clemens D., Troyanskaya, Olga G., Kretzler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814886/
https://www.ncbi.nlm.nih.gov/pubmed/23950145
http://dx.doi.org/10.1101/gr.155697.113