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Network properties derived from deep sequencing of human B-cell receptor repertoires delineate B-cell populations

The adaptive immune response selectively expands B- and T-cell clones following antigen recognition by B- and T-cell receptors (BCR and TCR), respectively. Next-generation sequencing is a powerful tool for dissecting the BCR and TCR populations at high resolution, but robust computational analyses a...

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Detalles Bibliográficos
Autores principales: Bashford-Rogers, Rachael J.M., Palser, Anne L., Huntly, Brian J., Rance, Richard, Vassiliou, George S., Follows, George A., Kellam, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814887/
https://www.ncbi.nlm.nih.gov/pubmed/23742949
http://dx.doi.org/10.1101/gr.154815.113