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Positive or negative allosteric modulation of metabotropic glutamate receptor 5 (mGluR5) does not alter expression of behavioral sensitization to methamphetamine

We investigated the role of metabotropic glutamate receptor type 5 (mGluR5) in methamphetamine-induced behavioral sensitization. The mGluR5 positive allosteric modulator (3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl) benzamide (CDPPB) and negative allosteric modulator fenobam were tested in separate expe...

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Detalles Bibliográficos
Autores principales: Kufahl, Peter R, Nemirovsky, Natali E, Watterson, Lucas R, Zautra, Nicholas, Olive, M Foster
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814922/
https://www.ncbi.nlm.nih.gov/pubmed/24358885
http://dx.doi.org/10.12688/f1000research.2-84.v1