IRF-4-Mediated CIITA Transcription Is Blocked by KSHV Encoded LANA to Inhibit MHC II Presentation

Peptides presentation to T cells by MHC class II molecules is of importance in initiation of immune response to a pathogen. The level of MHC II expression directly influences T lymphocyte activation and is often targeted by various viruses. Kaposi's sarcoma-associated herpesvirus (KSHV) encoded...

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Detalles Bibliográficos
Autores principales: Cai, Qiliang, Banerjee, Shuvomoy, Cervini, Amanda, Lu, Jie, Hislop, Andrew D., Dzeng, Richard, Robertson, Erle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814934/
https://www.ncbi.nlm.nih.gov/pubmed/24204280
http://dx.doi.org/10.1371/journal.ppat.1003751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814934/
https://www.ncbi.nlm.nih.gov/pubmed/24204280
http://dx.doi.org/10.1371/journal.ppat.1003751

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