Zonated induction of autophagy and mitochondrial spheroids limits acetaminophen-induced necrosis in the liver()

Acetaminophen (APAP) overdose is the most frequent cause of acute liver failure in the US and many western countries. It is well known that APAP induces mitochondrial damage to trigger centrilobular necrosis. Emerging evidence suggests that autophagic removal of damaged mitochondria may protect agai...

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Detalles Bibliográficos
Autores principales: Ni, Hong-Min, Williams, Jessica A, Jaeschke, Hartmut, Ding, Wen-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Graphic Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814950/
https://www.ncbi.nlm.nih.gov/pubmed/24191236
http://dx.doi.org/10.1016/j.redox.2013.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814950/
https://www.ncbi.nlm.nih.gov/pubmed/24191236
http://dx.doi.org/10.1016/j.redox.2013.08.005

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