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Zonated induction of autophagy and mitochondrial spheroids limits acetaminophen-induced necrosis in the liver()
Acetaminophen (APAP) overdose is the most frequent cause of acute liver failure in the US and many western countries. It is well known that APAP induces mitochondrial damage to trigger centrilobular necrosis. Emerging evidence suggests that autophagic removal of damaged mitochondria may protect agai...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814950/ https://www.ncbi.nlm.nih.gov/pubmed/24191236 http://dx.doi.org/10.1016/j.redox.2013.08.005 |