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Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells()

Neurons rely on the release and subsequent cleavage of GSH to cysteinylglycine (CysGly) by astrocytes in order to maintain optimal intracellular GSH levels. In neurodegenerative diseases characterised by oxidative stress, neurons need an optimal GSH supply to defend themselves against free radicals...

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Detalles Bibliográficos
Autores principales: Steele, Megan L., Fuller, Stacey, Patel, Mili, Kersaitis, Cindy, Ooi, Lezanne, Münch, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814960/
https://www.ncbi.nlm.nih.gov/pubmed/24191238
http://dx.doi.org/10.1016/j.redox.2013.08.006