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Characterization and Prediction of Haploinsufficiency Using Systems-Level Gene Properties in Yeast
Variation in gene copy number can significantly affect organism fitness. When one allele is missing in a diploid, the phenotype can be compromised because of haploinsufficiency. In this work, we identified associations between Saccharomyces cerevisiae gene properties and genome-scale haploinsufficie...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815059/ https://www.ncbi.nlm.nih.gov/pubmed/24048642 http://dx.doi.org/10.1534/g3.113.008144 |