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The potential of the human immune system to develop broadly neutralizing HIV-1 antibodies: implications for vaccine development

OBJECTIVES AND DESIGN: Developing an effective HIV-1 vaccine that elicits broadly neutralizing HIV-1 human antibodies (bnAbs) remains a challenging goal. Extensive studies on HIV-1 have revealed various strategies employed by the virus to escape host immune surveillance. Here, we investigated the hu...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Yuan, Tingting, Li, Jingjing, Zhang, Yanyu, Xu, Jianqing, Shao, Yiming, Chen, Zhiwei, Zhang, Mei-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815086/
https://www.ncbi.nlm.nih.gov/pubmed/24100711
http://dx.doi.org/10.1097/QAD.0000000000000015