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A Rapid Gene Delivery–Based Mouse Model for Early-Stage Alzheimer Disease–Type Tauopathy

The perforant pathway projection from the entorhinal cortex (EC) to the hippocampal dentate gyrus is critically important for long-term memory and develops tau and amyloid pathologies and progressive degeneration starting in the early stages of Alzheimer disease (AD). However, perforant pathway func...

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Detalles Bibliográficos
Autores principales: Siman, Robert, Lin, Yin-Guo, Malthankar-Phatak, Gauri, Dong, Yina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815088/
https://www.ncbi.nlm.nih.gov/pubmed/24128676
http://dx.doi.org/10.1097/NEN.0000000000000006