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Enhancing the Function of CD34(+) Cells by Targeting Plasminogen Activator Inhibitor-1

Previously, we showed that transient inhibition of TGF- β1 resulted in correction of key aspects of diabetes-induced CD34(+) cell dysfunction. In this report, we examine the effect of transient inhibition of plasminogen activator inhibitor-1 (PAI-1), a major gene target of TGF-β1 activation. Using g...

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Detalles Bibliográficos
Autores principales: Hazra, Sugata, Stepps, Valerie, Bhatwadekar, Ashay D., Caballero, Sergio, Boulton, Michael E., Higgins, Paul J., Nikonova, Elena V., Pepine, Carl J., Thut, Catherine, Finney, Eva M., Stone, David J., Bartelmez, Stephen H., Grant, Maria B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815099/
https://www.ncbi.nlm.nih.gov/pubmed/24223881
http://dx.doi.org/10.1371/journal.pone.0079067