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Enhancing the Function of CD34(+) Cells by Targeting Plasminogen Activator Inhibitor-1
Previously, we showed that transient inhibition of TGF- β1 resulted in correction of key aspects of diabetes-induced CD34(+) cell dysfunction. In this report, we examine the effect of transient inhibition of plasminogen activator inhibitor-1 (PAI-1), a major gene target of TGF-β1 activation. Using g...
Autores principales: | Hazra, Sugata, Stepps, Valerie, Bhatwadekar, Ashay D., Caballero, Sergio, Boulton, Michael E., Higgins, Paul J., Nikonova, Elena V., Pepine, Carl J., Thut, Catherine, Finney, Eva M., Stone, David J., Bartelmez, Stephen H., Grant, Maria B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815099/ https://www.ncbi.nlm.nih.gov/pubmed/24223881 http://dx.doi.org/10.1371/journal.pone.0079067 |
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