Concerted In Vitro Trimming of Viral HLA-B27-Restricted Ligands by Human ERAP1 and ERAP2 Aminopeptidases

In the classical human leukocyte antigen (HLA) class I antigen processing and presentation pathway, the antigenic peptides are generated from viral proteins by multiple proteolytic cleavages of the proteasome (and in some cases other cytosolic proteases) and transported to the endoplasmic reticulum...

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Detalles Bibliográficos
Autores principales: Lorente, Elena, Barriga, Alejandro, Johnstone, Carolina, Mir, Carmen, Jiménez, Mercedes, López, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815102/
https://www.ncbi.nlm.nih.gov/pubmed/24223975
http://dx.doi.org/10.1371/journal.pone.0079596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815102/
https://www.ncbi.nlm.nih.gov/pubmed/24223975
http://dx.doi.org/10.1371/journal.pone.0079596

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