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Study of the HIV-2 Env Cytoplasmic Tail Variability and Its Impact on Tat, Rev and Nef

BACKGROUND: The HIV-2 env’s 3’ end encodes the cytoplasmic tail (CT) of the Env protein. This genomic region also encodes the rev, Tat and Nef protein in overlapping reading frames. We studied the variability in the CT coding region in 46 clinical specimens and in 2 reference strains by sequencing a...

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Detalles Bibliográficos
Autores principales: Bakouche, Nordine, Vandenbroucke, Anne-Thérèse, Goubau, Patrick, Ruelle, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815105/
https://www.ncbi.nlm.nih.gov/pubmed/24223892
http://dx.doi.org/10.1371/journal.pone.0079129