Roscovitine-induced Apoptosis in Neutrophils and Neutrophil Progenitors Is Regulated by the Bcl-2-Family Members Bim, Puma, Noxa and Mcl-1

Neutrophil granulocyte (neutrophil) apoptosis plays a key role in determining inflammation in infectious and non-infectious settings. Recent work has shown that inhibitors of cyclin-dependent kinases (cdk) such as roscovitine can potently induce neutrophil apoptosis and reduce inflammation. Using a...

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Detalles Bibliográficos
Autores principales: Gautam, Sanjivan, Kirschnek, Susanne, Wiesmeier, Michael, Vier, Juliane, Häcker, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815126/
https://www.ncbi.nlm.nih.gov/pubmed/24223929
http://dx.doi.org/10.1371/journal.pone.0079352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815126/
https://www.ncbi.nlm.nih.gov/pubmed/24223929
http://dx.doi.org/10.1371/journal.pone.0079352

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