Influence of Clonidine and Ketamine on m-RNA Expression in a Model of Opioid-Induced Hyperalgesia in Mice

BACKGROUND: We investigated the influence of morphine and ketamine or clonidine in mice on the expression of genes that may mediate pronociceptive opioid effects. MATERIAL AND METHODS: C57BL/6 mice received morphine injections thrice daily using increasing doses (5-20mg∙kg(-1)) for 3 days (sub-acute...

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Detalles Bibliográficos
Autores principales: Ohnesorge, Henning, Feng, Zhiying, Zitta, Karina, Steinfath, Markus, Albrecht, Martin, Bein, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815130/
https://www.ncbi.nlm.nih.gov/pubmed/24223972
http://dx.doi.org/10.1371/journal.pone.0079567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815130/
https://www.ncbi.nlm.nih.gov/pubmed/24223972
http://dx.doi.org/10.1371/journal.pone.0079567

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