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Influence of Clonidine and Ketamine on m-RNA Expression in a Model of Opioid-Induced Hyperalgesia in Mice
BACKGROUND: We investigated the influence of morphine and ketamine or clonidine in mice on the expression of genes that may mediate pronociceptive opioid effects. MATERIAL AND METHODS: C57BL/6 mice received morphine injections thrice daily using increasing doses (5-20mg∙kg(-1)) for 3 days (sub-acute...
Autores principales: | Ohnesorge, Henning, Feng, Zhiying, Zitta, Karina, Steinfath, Markus, Albrecht, Martin, Bein, Berthold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815130/ https://www.ncbi.nlm.nih.gov/pubmed/24223972 http://dx.doi.org/10.1371/journal.pone.0079567 |
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