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Axonal Regeneration after Sciatic Nerve Lesion Is Delayed but Complete in GFAP- and Vimentin-Deficient Mice

Peripheral axotomy of motoneurons triggers Wallerian degeneration of injured axons distal to the lesion, followed by axon regeneration. Centrally, axotomy induces loss of synapses (synaptic stripping) from the surface of lesioned motoneurons in the spinal cord. At the lesion site, reactive Schwann c...

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Detalles Bibliográficos
Autores principales: Berg, Alexander, Zelano, Johan, Pekna, Marcela, Wilhelmsson, Ulrika, Pekny, Milos, Cullheim, Staffan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815133/
https://www.ncbi.nlm.nih.gov/pubmed/24223940
http://dx.doi.org/10.1371/journal.pone.0079395