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Alterations in the Cell Cycle in the Cerebellum of Hyperbilirubinemic Gunn Rat: A Possible Link with Apoptosis?

Severe hyperbilirubinemia causes neurological damage both in humans and rodents. The hyperbilirubinemic Gunn rat shows a marked cerebellar hypoplasia. More recently bilirubin ability to arrest the cell cycle progression in vascular smooth muscle, tumour cells, and, more importantly, cultured neurons...

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Detalles Bibliográficos
Autores principales: Robert, María Celeste, Furlan, Giulia, Rosso, Natalia, Gambaro, Sabrina Eliana, Apitsionak, Faina, Vianello, Eleonora, Tiribelli, Claudio, Gazzin, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815147/
https://www.ncbi.nlm.nih.gov/pubmed/24223883
http://dx.doi.org/10.1371/journal.pone.0079073