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Effects of l-DOPA on striatal iodine-123-FP-CIT binding and behavioral parameters in the rat

PURPOSE: The effect of clinical l-3,4-dihydroxyphenylalanine (l-DOPA) doses on the binding of [(123)I]N-Ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane ([(123)I]FP-CIT) to the rat dopamine transporter (DAT) was investigated using small animal single-photon emission computed tomography. MA...

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Detalles Bibliográficos
Autores principales: Nikolaus, Susanne, Beu, Markus, Hautzel, Hubertus, De Souza Silva, Angelica M., Antke, Christina, Wirrwar, Andreas, Huston, Joseph P., Müller, Hans-Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815148/
https://www.ncbi.nlm.nih.gov/pubmed/23982164
http://dx.doi.org/10.1097/MNM.0b013e3283657404