γ-Secretase Components as Predictors of Breast Cancer Outcome

γ-secretase is a large ubiquitously expressed protease complex composed of four core subunits: presenilin, Aph1, PEN-2, and nicastrin. The function of γ-secretase in the cells is to proteolytically cleave various proteins within their transmembrane domains. Presenilin and Aph1 occur as alternative v...

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Detalles Bibliográficos
Autores principales: Peltonen, Hanna M., Haapasalo, Annakaisa, Hiltunen, Mikko, Kataja, Vesa, Kosma, Veli-Matti, Mannermaa, Arto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815159/
https://www.ncbi.nlm.nih.gov/pubmed/24223915
http://dx.doi.org/10.1371/journal.pone.0079249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815159/
https://www.ncbi.nlm.nih.gov/pubmed/24223915
http://dx.doi.org/10.1371/journal.pone.0079249

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