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Agonist Antagonist Interactions at the Rapidly Desensitizing P2X3 Receptor

P2X3 receptors (P2XRs), as members of the purine receptor family, are deeply involved in chronic pain sensation and therefore, specific, competitive antagonists are of great interest for perspective pain management. Heretofore, Schild plot analysis has been commonly used for studying the interaction...

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Detalles Bibliográficos
Autores principales: Helms, Nick, Kowalski, Maria, Illes, Peter, Riedel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815160/
https://www.ncbi.nlm.nih.gov/pubmed/24223907
http://dx.doi.org/10.1371/journal.pone.0079213