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Helicobacter pylori Protein JHP0290 Binds to Multiple Cell Types and Induces Macrophage Apoptosis via Tumor Necrosis Factor (TNF)-Dependent and Independent Pathways

Activated macrophages at the sub-mucosal space play a major role in generating innate immune responses during H. pylori infection. Final disease outcome largely depends on how H. pylori and bacterium-derived products modulate macrophage responses. Here, we report that JHP0290, a functionally unknown...

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Detalles Bibliográficos
Autores principales: Pathak, Sushil Kumar, Tavares, Raquel, de Klerk, Nele, Spetz, Anna-Lena, Jonsson, Ann-Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815203/
https://www.ncbi.nlm.nih.gov/pubmed/24223737
http://dx.doi.org/10.1371/journal.pone.0077872