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Kinetics of MDR Transport in Tumor-Initiating Cells

Multidrug resistance (MDR) driven by ABC (ATP binding cassette) membrane transporters is one of the major causes of treatment failure in human malignancy. MDR capacity is thought to be unevenly distributed among tumor cells, with higher capacity residing in tumor-initiating cells (TIC) (though oppos...

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Detalles Bibliográficos
Autores principales: Koshkin, Vasilij, Yang, Burton B., Krylov, Sergey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815210/
https://www.ncbi.nlm.nih.gov/pubmed/24223908
http://dx.doi.org/10.1371/journal.pone.0079222