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Reversal Learning and Associative Memory Impairments in a BACHD Rat Model for Huntington Disease

Chorea and psychiatric symptoms are hallmarks of Huntington disease (HD), a neurodegenerative disorder, genetically characterized by the presence of expanded CAG repeats (>35) in the HUNTINGTIN (HTT) gene. HD patients present psychiatric symptoms prior to the onset of motor symptoms and we recent...

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Detalles Bibliográficos
Autores principales: Abada, Yah-se K., Nguyen, Huu Phuc, Ellenbroek, Bart, Schreiber, Rudy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815226/
https://www.ncbi.nlm.nih.gov/pubmed/24223692
http://dx.doi.org/10.1371/journal.pone.0071633