Targeted over-expression of endothelin-1 in astrocytes leads to more severe brain damage and vasospasm after subarachnoid hemorrhage

BACKGROUND: Endothelin-1 (ET-1) is a potent vasoconstrictor, and astrocytic ET-1 is reported to play a role in the pathogenesis of cerebral ischemic injury and cytotoxic edema. However, it is still unknown whether astrocytic ET-1 also contributes to vasogenic edema and vasospasm during subarachnoid...

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Detalles Bibliográficos
Autores principales: Yeung, Patrick KK, Shen, Jiangang, Chung, Stephen SM, Chung, Sookja K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815232/
https://www.ncbi.nlm.nih.gov/pubmed/24156724
http://dx.doi.org/10.1186/1471-2202-14-131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815232/
https://www.ncbi.nlm.nih.gov/pubmed/24156724
http://dx.doi.org/10.1186/1471-2202-14-131

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