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Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients’ bed

BACKGROUND: Major goals in translational oncology are to reduce systemic toxicity of current anticancer strategies and improve effectiveness. An extremely efficient cancer cell mechanism to avoid and/or reduce the effects of highly cytotoxic drugs is the establishment of an acidic microenvironment,...

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Detalles Bibliográficos
Autores principales: Ferrari, Stefano, Perut, Francesca, Fagioli, Franca, Brach Del Prever, Adalberto, Meazza, Cristina, Parafioriti, Antonina, Picci, Piero, Gambarotti, Marco, Avnet, Sofia, Baldini, Nicola, Fais, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815282/
https://www.ncbi.nlm.nih.gov/pubmed/24156349
http://dx.doi.org/10.1186/1479-5876-11-268