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Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients’ bed
BACKGROUND: Major goals in translational oncology are to reduce systemic toxicity of current anticancer strategies and improve effectiveness. An extremely efficient cancer cell mechanism to avoid and/or reduce the effects of highly cytotoxic drugs is the establishment of an acidic microenvironment,...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815282/ https://www.ncbi.nlm.nih.gov/pubmed/24156349 http://dx.doi.org/10.1186/1479-5876-11-268 |