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Expression of Innate Immunity Genes and Damage of Primary Human Pancreatic Islets by Epidemic Strains of Echovirus: Implication for Post-Virus Islet Autoimmunity

Three large-scale Echovirus (E) epidemics (E4,E16,E30), each differently associated to the acute development of diabetes related autoantibodies, have been documented in Cuba. The prevalence of islet cell autoantibodies was moderate during the E4 epidemic but high in the E16 and E30 epidemic. The aim...

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Detalles Bibliográficos
Autores principales: Sarmiento, Luis, Frisk, Gun, Anagandula, Mahesh, Cabrera-Rode, Eduardo, Roivainen, Merja, Cilio, Corrado M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815302/
https://www.ncbi.nlm.nih.gov/pubmed/24223733
http://dx.doi.org/10.1371/journal.pone.0077850