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Bioengineered nisin derivatives with enhanced activity in complex matrices

Nisin A is the best known and most extensively characterized lantibiotic. As it is ribosomally synthesized, bioengineering‐based strategies can be used to generate variants. We have previously demonstrated that bioengineering of the hinge region of nisin A can result in the generation of variants wi...

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Detalles Bibliográficos
Autores principales: Rouse, Susan, Field, Des, Daly, Karen M., O'Connor, Paula M., Cotter, Paul D., Hill, Colin, Ross, R. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815327/
https://www.ncbi.nlm.nih.gov/pubmed/22260415
http://dx.doi.org/10.1111/j.1751-7915.2011.00324.x