Non-Invasive Prenatal Testing of Trisomy 18 by an Epigenetic Marker in First Trimester Maternal Plasma

BACKGROUND: Quantification of cell-free fetal DNA by methylation-based DNA discrimination has been used in non-invasive prenatal testing of fetal chromosomal aneuploidy. The maspin (Serpin peptidase inhibitor, clade B (ovalbumin), member 5; SERPINB5) gene, located on chromosome 18q21.33, is hypometh...

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Detalles Bibliográficos
Autores principales: Lee, Da Eun, Kim, Shin Young, Lim, Ji Hyae, Park, So Yeon, Ryu, Hyun Mee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815335/
https://www.ncbi.nlm.nih.gov/pubmed/24223769
http://dx.doi.org/10.1371/journal.pone.0078136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815335/
https://www.ncbi.nlm.nih.gov/pubmed/24223769
http://dx.doi.org/10.1371/journal.pone.0078136

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