CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner

Treg cells are critical for the prevention of autoimmune diseases and are thus prime candidates for cell-based clinical therapy. However, human Treg cells are “plastic”, and are able to produce IL-17 under inflammatory conditions. Here, we identify and characterize the human Treg subpopulation that...

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Detalles Bibliográficos
Autores principales: Afzali, Behdad, Mitchell, Peter J, Edozie, Francis C, Povoleri, Giovanni AM, Dowson, Sophie E, Demandt, Laura, Walter, Gina, Canavan, James B, Scotta, Cristiano, Menon, Bina, Chana, Prabhjoat S, Khamri, Wafa, Kordasti, Shahram Y, Heck, Susanne, Grimbacher, Bodo, Tree, Timothy, Cope, Andrew P, Taams, Leonie S, Lechler, Robert I, John, Susan, Lombardi, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Cellular Immune Response
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815561/
https://www.ncbi.nlm.nih.gov/pubmed/23677517
http://dx.doi.org/10.1002/eji.201243296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815561/
https://www.ncbi.nlm.nih.gov/pubmed/23677517
http://dx.doi.org/10.1002/eji.201243296

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