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Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury

Podocytes are highly specialized epithelial cells with complex actin cytoskeletal architecture crucial for maintenance of the glomerular filtration barrier. The mammalian Rho GTPases Rac1 and Cdc42 are molecular switches that control many cellular processes, but are best known for their roles in the...

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Detalles Bibliográficos
Autores principales: Blattner, Simone M., Hodgin, Jeffrey B., Nishio, Masashi, Wylie, Stephanie, Saha, Jharna, Soofi, Abdul, Vining, Courtenay, Randolph, Ann, Herbach, Nadja, Wanke, Ruediger, Atkins, Kevin B., Kang, Hee Gyung, Henger, Anna, Brakebusch, Cord, Holzman, Lawrence B., Kretzler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815690/
https://www.ncbi.nlm.nih.gov/pubmed/23677246
http://dx.doi.org/10.1038/ki.2013.175