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Sequence‐ and activity‐based screening of microbial genomes for novel dehalogenases

Dehalogenases are environmentally important enzymes that detoxify organohalogens by cleaving their carbon‐halogen bonds. Many microbial genomes harbour enzyme families containing dehalogenases, but a sequence‐based identification of genuine dehalogenases with high confidence is challenging because o...

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Detalles Bibliográficos
Autores principales: Chan, Wing Yiu, Wong, Max, Guthrie, Jennifer, Savchenko, Alexei V., Yakunin, Alexander F., Pai, Emil F., Edwards, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815952/
https://www.ncbi.nlm.nih.gov/pubmed/21255311
http://dx.doi.org/10.1111/j.1751-7915.2009.00155.x