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Evaluating the Immunogenicity of Protein Drugs by Applying In Vitro MHC Binding Data and the Immune Epitope Database and Analysis Resource

The immune system has evolved to become highly specialized in recognizing and responding to pathogens and foreign molecules. Specifically, the function of HLA class II is to ensure that a sufficient sample of peptides derived from foreign molecules is presented to T cells. This leads to an important...

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Detalles Bibliográficos
Autores principales: Paul, Sinu, Kolla, Ravi V., Sidney, John, Weiskopf, Daniela, Fleri, Ward, Kim, Yohan, Peters, Bjoern, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816028/
https://www.ncbi.nlm.nih.gov/pubmed/24222776
http://dx.doi.org/10.1155/2013/467852